| Abstrakt: |
The connection between alpha 1-proteinase inhibitor variants and immunity disorders in patients with chronic obstructive bronchitis is considered in the article. As a result of investigation disorders of both T- and B-immunity systems were found. They consisted in decrease of the content and proliferative activity of T-lymphocytes, changes in their populational composition, dysfunction of B-lymphocytes, dysimmunoglobulinemia. These changes were more pronounced in allele M3+ carriers constituting the risk group on chronic lung diseases. |
