The role of HLA-DQ antigens in the induction of cytotoxic T lymphocytes.

Autor: Porubská S; Institute of Immunology, Faculty of Medicine, Comenius University, Bratislava., Buc M, Bencová M, Sausová E
Jazyk: angličtina
Zdroj: Folia biologica [Folia Biol (Praha)] 1993; Vol. 39 (5), pp. 256-61.
Abstrakt: Investigating three pairs of HLA-DR (DRB1) identical unrelated persons on the induction of cytotoxic T lymphocytes (CTL) it was found that HLA-DQ antigens provided slight proliferative stimulus which was, however, sufficient for the generation of CTL. The results indicate that the HLA-DQ antigens do play a similar role in clinical bone marrow transplantation as the HLA-DR specificities.
Databáze: MEDLINE