| Autor: |
Weinmann P; Department of Nuclear Medicine, Avicenne University Hospital, Bobigny, France., Foult JM, Le Guludec D, Tamgac F, Rechtman D, Neuman A, Caillat-Vigneron N, Moretti JL |
| Jazyk: |
angličtina |
| Zdroj: |
European journal of nuclear medicine [Eur J Nucl Med] 1994 Mar; Vol. 21 (3), pp. 212-5. |
| DOI: |
10.1007/BF00188668 |
| Abstrakt: |
Two hundred and thirty-one patients underwent dual-isotope myocardial imaging (rest thallium-201 followed by stress technetium-99m sestamibi). The feasibility of the procedure was excellent: camera scheduling flexibility was improved and the duration of the procedure was less than that of a classical stress-redistribution procedure. Interpretation of defects due to image attenuation was facilitated by the different attenuation properties of 201Tl and 99mTc-sestamibi in 11 of 19 patients. 201Tl cross-over on 99mTc was found to be 15% +/- 3% with doses of 201Tl and 99mTc-sestamibi of 3 and 10 mCi, respectively, and 7% +/- 2% with doses of 3 and 20 mCi. This protocol should preferentially be reserved for patients with a history of myocardial infarction and/or a basal left ventricular dysfunction, in whom assessment of myocardial viability is of major interest. Extensive clinical validation of the dual-isotope procedure is required and optimal acquisition and reconstruction parameters should be established. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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