Blood transfusion and survival in colorectal cancer.

Autor: Sibbering DM; Department of Surgery, University Hospital, Queen's Medical Centre, Nottingham, United Kingdom., Locker AP, Hardcastle JD, Armitage NC
Jazyk: angličtina
Zdroj: Diseases of the colon and rectum [Dis Colon Rectum] 1994 Apr; Vol. 37 (4), pp. 358-63.
DOI: 10.1007/BF02053597
Abstrakt: Purpose: This study examined the effect of blood transfusion on the prognosis of patients undergoing surgery for colorectal cancer.
Methods: Potentially curative resections for colorectal cancer were performed in 266 patients who were followed prospectively, with a minimum follow-up of 41 months. They were divided into transfused (n = 121) and nontransfused (n = 145) groups according to their perioperative blood transfusion requirements.
Results: There were significantly more rectal tumors (chi 2 = 9.5, df = 1, P = 0.002) and fixed tumors (chi 2 = 4.5, df = 1, P = 0.03) in the transfused group. There was no statistically significant difference between the two groups with regard to recurrence-free survival (chi 2 = 1.1, df = 1, P = 0.3) and overall survival (chi 2 = 2.8, df = 1, P = 0.09).
Conclusion: In this study we have found no statistically significant effect of perioperative blood transfusion on the prognosis of colorectal cancer patients.
Databáze: MEDLINE
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