| Autor: |
Romanyshyn LA; Department of Biochemistry, Wallace Laboratories, Cranbury, New Jersey 08512., Wichmann JK, Kucharczyk N, Sofia RD |
| Jazyk: |
angličtina |
| Zdroj: |
Therapeutic drug monitoring [Ther Drug Monit] 1994 Feb; Vol. 16 (1), pp. 83-9. |
| DOI: |
10.1097/00007691-199402000-00014 |
| Abstrakt: |
An isocratic liquid-chromatographic method employing one extraction step and a 4.6 mm x 150 mm Spherisorb ODS2, 3 microns high-performance liquid chromatography (HPLC) column using ultraviolet (UV)-absorbance detection at 210 nm has been developed for quantitation of felbamate (FBM) and three felbamate metabolites in 0.100-ml aliquots of human plasma. The linear quantitation range for FBM and the two hydroxy metabolites is 0.781-200 micrograms/ml, and that for the monocarbamate metabolite is 0.391-200 micrograms/ml. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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