Effects of butylated hydroxyanisole in Drosophila melanogaster.
| Autor: | Miyagi MP, Goodheart CR |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Mutation research [Mutat Res] 1976 Jan; Vol. 40 (1), pp. 37-42. |
| DOI: | 10.1016/0165-1218(76)90020-3 |
| Abstrakt: | The standard sex-linked recessive lethal test using "Basc" virgin females and treated Canton S males was used to test potential mutagenicity of ingested butylated hydroxyanisole (BHA) on mature spermatozoa. Ethyl methanesulfonate (EMS) was employed as a positive control and at lower concentrations a roughly linear dose response curve resulted. Flies treated with BHA yielded no higher frequency of sex-linked recessive lethals than did control flies, and statistical analysis confirmed that a high confidence level, the BHA treatment used did not double the spontaneous frequency of sex-linked recessive lethals. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|