| Autor: |
Farag TI; Kuwait Medical Genetics Centre, Maternity Hospital Liaison Genetic Clinic., al-Awadi SA, el-Badramary MH, Aref MA, Kasrawi B, Krishna Murthy DS, el-Khalifa MY, Yadav G, Marafie MJ, Bastaki L, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical genetics [Clin Genet] 1993 Dec; Vol. 44 (6), pp. 329-34. |
| DOI: |
10.1111/j.1399-0004.1993.tb03910.x |
| Abstrakt: |
In this preliminary report we summarize the results of a 4-year multidisciplinary systematic, etiological clinicogenetic survey of 400 institutionalized mentally retarded patients in Kuwait. All had an intelligence quotient below 50. A constitutional disorder, as the direct cause of the mental retardation, was found in 203 patients (50.75%)): a chromosomal abnormality in 37 (9.25%), Mendelian disorders in 137 (34.25%), MCA/MR in 22 (5.55%) and CNS malformations in 7 cases (1.75%). In 157 patients (39.35%) a pre-, peri or postnatal cause was ascertained. No etiological diagnosis was detected in 40 patients (10%). A detailed analysis of the "disease profile" is given and compared with the results of previous diagnostic genetic surveys among different institutionalized mentally retarded populations in Western and developing countries. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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