| Autor: |
Pistello M; Department of Biomedicine, University of Pisa, Italy., Maggi F, Vatteroni L, Cecconi N, Panicucci F, Bresci GP, Gambardella L, Taddei M, Bionda A, Tuoni M, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical microbiology [J Clin Microbiol] 1994 Jan; Vol. 32 (1), pp. 232-4. |
| DOI: |
10.1128/jcm.32.1.232-234.1994 |
| Abstrakt: |
Hepatitis C viruses (HCV) present in 110 Italian patients were characterized by genotype-specific PCRs. Among the 65 cases of community-acquired hepatitis, HCV genotype II was dominant (60%), followed by genotypes IV (15%), III (11%), and I (3%). Among the 45 hemophilia-associated cases, the distribution of the four HCV genotypes was markedly different: genotype I was the most prevalent (61%), followed by genotypes II (25%), III (4%), and IV (2%). Double infections were observed in eight patients. Two HCV remained unclassified. For the 45 community-acquired cases from which a liver biopsy was available, genotype II was associated with more severe liver damage than the other types. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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