Autor: |
Hovens JE; Psychiatrisch Ziekenhuis H.C. Rümke groep, locatie Zeist., Vogtländer LM, Verhoeve HA, Thunnissen PL |
Jazyk: |
Dutch; Flemish |
Zdroj: |
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 1994 Feb 12; Vol. 138 (7), pp. 363-5. |
Abstrakt: |
A 38-year-old woman was treated for mutism with clozapine. After a week liver function disturbances developed, which disappeared when the treatment was discontinued. Histopathological investigation of a liver biopsy specimen revealed extensive liver cell necrosis. So far two patients have been described with cholestatic jaundice induced by clozapine, and one patient with toxic hepatitis due to clozapine. |
Databáze: |
MEDLINE |
Externí odkaz: |
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