| Autor: |
Ryabova ID, Gorneva GA, Ovchinnikov YA |
| Jazyk: |
angličtina |
| Zdroj: |
Biochimica et biophysica acta [Biochim Biophys Acta] 1975 Aug 05; Vol. 401 (1), pp. 109-18. |
| DOI: |
10.1016/0005-2736(75)90345-4 |
| Abstrakt: |
The antimicrobial action of valinomycin relative to the K+ and Na+ contents of the medium has been investigated in several species of bacteria, particularly in Streptococcus faecalis, which effects energy-linked transport exclusively via degradation of glycolytic ATP, Micrococcus lysodeikticus, effecting active ion transport by respiration and Staphylococcus aureus, the energy-dependent ion transport of which is due to both glycolytic ATP degradation and respiration. It was demonstrated that valinomycin does not act on K+ transport in the glycolysing cells in the same manner as it does on respiring cells under similar conditions. Addition of valinomycin to respiring cells leads to an increase in K+ influx against the concentrational gradient in both growing and resting cells. In contrast to this, antibiotic-treated glycolysing cells experience passive K+ outflow down the concentrational gradient. It was thus concluded that the electrical potential cannot be the driving force for the energy-linked K+ transport in glycolysing cells. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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