| Autor: |
Blitzer PH; Radiation Therapy Regional Center, Fort Myers., Dosoretz DE, Katin MJ, Rubenstein JH, Harwin WN, Raymond MG, Teufel TE, Seidenstein L, Mangano MM, Salenius SA, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of the Florida Medical Association [J Fla Med Assoc] 1994 Jun; Vol. 81 (6), pp. 403-7. |
| Abstrakt: |
Patients unable to undergo a pancreatoduodenectomy for adenocarcinoma of the pancreas are often treated with radiation therapy. A randomized trial by the Gastrointestinal Tumor Study Group has shown an advantage in combining it with chemotherapy. A similar size retrospective study at a large community radiation therapy center assessed this finding in the nonprotocol setting. The study population consisted of 86 patients treated with primary radiation therapy between 1982 and 1992; 62 of them also received chemotherapy. The overall probability of survival was 39% and 13% at 12 and 24 months respectively. Patients receiving chemotherapy had a significantly (p = .018) longer survival (44% versus 25% at 12 months). Results confirm the Study Group's findings and suggest that they be applied to the community setting. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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