[Neuroradiological findings in perinatally HIV-infected children].

Autor: Spreer J; Radiologische Abteilung, Universitätsklinik Köln., Enenkel-Stoodt S, Funk M, Fiedler A, de Simone A, Hacker H
Jazyk: němčina
Zdroj: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin [Rofo] 1994 Aug; Vol. 161 (2), pp. 106-12.
DOI: 10.1055/s-2008-1032502
Abstrakt: The neuroradiological studies (CT, MRI, angiography) in 21 children with perinatal HIV infection were reviewed retrospectively. No patient showed an intracranial mass lesion; after intravenous contrast medium application there was no case with disturbed blood-brain barrier. Common non-specific findings were atrophy and delayed myelination. In 7 cases atrophy was combined with multifocal nearly symmetric white matter lesions, which characteristically spared the U-fibres. Further findings included an intramedullary ring-shaped structure in the cervical cord, an AIDS-associated vasculopathy and symmetric calcifications in the basal ganglia. The spectrum of neuroradiological findings in paediatric AIDS patients differs from that in adults. Knowledge of these age-specific findings is important because the number of HIV-infected children is rising.
Databáze: MEDLINE