[Development of super-resistance to hypoxic hypoxia during adaptation to short-term stress].

Autor: Meerson FZ, Miniaĭlenko TD, Pozharov VP
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1993 Feb; Vol. 115 (2), pp. 132-5.
Abstrakt: Adaptation to intermittent short-term immobilization stress exposure increases the resistance of rats to hypoxic hypoxia. This was evidenced by the fact that in acute experiments in respiration with gas-mixture containing 6% of oxygen, the mortality of control rats was 65% compared with 10% of that of adapted rats. It has been estimated that this protective cross-effect of adaptation to stress is due to more stable and efficient mobilization of external respiration in adapted animals, and to a greater extent, to the fact that adapted rats tissues have gained a capacity of extracting more oxygen from hypoxemic blood compared to control animals. The role of previously stated phenomenon of adaptive stabilization of structures in superresistance to hypoxic hypoxia is discussed.
Databáze: MEDLINE