Osteonecrosis following treatment for Hodgkin's disease.

Autor: Ellis J; Department of Medicine, Crosshouse Hospital, Kilmarnock, Scotland, UK., MacLeod U, Sammon D, Lindsay E, Erskine JG
Jazyk: angličtina
Zdroj: Clinical and laboratory haematology [Clin Lab Haematol] 1994 Mar; Vol. 16 (1), pp. 3-8.
DOI: 10.1111/j.1365-2257.1994.tb00381.x
Abstrakt: Osteonecrosis is usually considered to be a minor and rare late sequelae of treatment for Hodgkin's Disease (HD). However, over ten years six patients out of a total of 53 patients treated for HD at the haematology department of a district general hospital developed osteonecrosis, an incidence of 11.3%. Routine isotope bone scanning of patients produced two further asymptomatic cases. These results suggest a higher incidence than previously suspected of a problem which caused our patients considerable morbidity. Further measures are required to identify and adequately treat a significant cause of late morbidity following chemotherapy for HD.
Databáze: MEDLINE