| Autor: |
Plourde PJ; Department of Medical Microbiology, University of Nairobi, Kenya., Pepin J, Agoki E, Ronald AR, Ombette J, Tyndall M, Cheang M, Ndinya-Achola JO, D'Costa LJ, Plummer FA |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of infectious diseases [J Infect Dis] 1994 Aug; Vol. 170 (2), pp. 313-7. |
| DOI: |
10.1093/infdis/170.2.313 |
| Abstrakt: |
Genital ulcers are implicated as a risk factor enhancing susceptibility to human immunodeficiency virus type 1 (HIV-1) infection. A prospective study to determine the incidence of and risk factors associated with acquisition of HIV-1 in women with genital ulcers was done. HIV-1-seronegative women with genital ulcers attending a clinic for sexually transmitted diseases in Nairobi were followed to HIV-1 seroconversion over a 6-month period. Of 81 women, 10 seroconverted to HIV-1. The crude 6-month incidence of HIV-1 infection was 12%. Risk factors associated with seroconversion included cervical ectopy (rate ratio [RR], 4.9; 95% confidence interval [CI], 1.5-15.6) and pelvic inflammatory disease (RR, 6.3; 95% CI, 1.9-20.4). Thus, cervical ectopy and pelvic inflammatory disease may increase susceptibility to HIV-1 in women with genital ulcers. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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