| Autor: |
Kondakova NV, Lisakovskiĭ SV, Sakharova VV, Koroleva OA, Dubinsksia VA, Nikolaeva SS |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy meditsinskoi khimii [Vopr Med Khim] 1994 Jul-Aug; Vol. 40 (4), pp. 46-50. |
| Abstrakt: |
The effect of ionizing radiation (gamma-irradiation of 60Co, doses from 10 Gy to 15 kGy) on human muscle tissue was studied using a biopsy material. Destructive alterations in muscle proteins were observed beginning from the dose of 1.0 kGy: appearance of new protein fractions with molecular mass 68-160 kDa and 18-36 kDa. Resistance of muscle proteins to the trypsin effect was unaltered, while the rate of pronase-induced hydrolysis was slightly increased, about 1.2-fold. Content of water and biomechanical properties of the tissue were unaltered, but the modulus of elasticity was decreased approximately 3-fold after treatment with maximal doses of the ionizing radiation used. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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