Rabies and bats in a rabies-endemic area of southern Africa: application of two commercial test kits for antigen and antibody detection.

Autor: Oelofsen MJ; Department of Virology, University of the Orange Free State, Bloemfontein, South Africa., Smith MS
Jazyk: angličtina
Zdroj: The Onderstepoort journal of veterinary research [Onderstepoort J Vet Res] 1993 Sep; Vol. 60 (3), pp. 257-60.
Abstrakt: In southern Africa, isolates of rabies-related viruses (i.e. Duvenhage virus and Lagos bat virus) have been made from insectivorous and frugivorous bats. As no recent formal bat virus survey has been reported in southern Africa, a survey of bats in rabies-endemic areas was undertaken. Five hundred and forty-seven bats (13 species) were collected from 21 localities in the Orange Free State, Lesotho and the northern Cape Province. None of the 190 bat sera tested using the "Trousse Platelia Rage" ELISA kit (Diagnostic Pasteur), had antibodies to rabies virus glycoprotein G. Rabies virus nucleocapsid antigen was also sought for in the brains of 530 bats (13 species) by means of the "Rapid rabies enzyme immunodiagnosis" (RREID) test (Diagnostics Pasteur). No positive results were obtained. These results show that bats are unlikely to play an important role as hosts of rabies in these parts of Africa, although a low rate of infection cannot be excluded.
Databáze: MEDLINE