| Autor: |
Fu D; Department of Biochemistry, Uniformed Services University of the Health Science, Bethesda, Maryland 20814., Beeler T, Dunn T |
| Jazyk: |
angličtina |
| Zdroj: |
Yeast (Chichester, England) [Yeast] 1994 Apr; Vol. 10 (4), pp. 515-21. |
| DOI: |
10.1002/yea.320100411 |
| Abstrakt: |
We have isolated, sequenced, mapped and disrupted a novel gene, CCC1, from Saccharomyces cerevisiae. This gene displays non-allelic complementation of the Ca(2+)-sensitive phenotype conferred by the csg1 mutation. The ability of this gene, in two copies per cell, to reverse the csg1 defect suggests it may have a role in regulating Ca2+ homeostasis. The sequence of CCC1 indicates that it encodes a 322 amino acid, membrane-associated protein. The CCC1 gene is located on the right arm of chromosome XII. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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