Spondyloarthropathies in circumpolar populations of Chukotka (Eskimos and Chukchi): epidemiology and clinical characteristics.

Autor:	Erdesz S; Department of Epidemiology and Genetics of Rheumatic Diseases, Institute of Rheumatology Russian Academy of Medical Sciences (RAMS), Moscow., Shubin SV, Shoch BP, Krylov MYu, Mylov NM, Chekalina NA, Benevolenskaya LI
Jazyk:	angličtina
Zdroj:	The Journal of rheumatology [J Rheumatol] 1994 Jun; Vol. 21 (6), pp. 1101-4.
Abstrakt:	Objective: We sought to determine the prevalence of HLA-B27 and the prevalence and nature of spondyloarthropathies in the native residents of Eastern Chukotka, Siberia, Russia. Methods: We conducted a cross sectional study with medical examination and interview of 464 of 640 (72.5%) native residents of 2 Eastern Chukotka settlements, Sireniki and Novo-Chaplino. Results: Among them were 212 Eskimos, 98 Chukchi and 154 subjects of mixed race. There were 2 subjects (0.4%) with ankylosing spondylitis, 2 with Reiter's syndrome, 2 with undifferentiated spondyloarthropathy and 1 with late onset pauciarticular juvenile arthritis consistent with spondyloarthropathy. Four of the subjects were Eskimos, 2 were of mixed race, and 1 was Chukchi. We found a high percentage of HLA-B27 antigen in the population, 32% in the native population overall, and 40% among the Eskimos. Conclusion: Our data complement other studies of circumpolar populations and reinforce the reported high prevalence of spondyloarthropathy and HLA-B27 among those people.
Databáze:	MEDLINE
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