High-dose narcotic anesthesia using sufentanil in swine for cardiac catheterization and electrophysiologic studies.

Autor: Schumann RE; Medical University of South Carolina, South Carolina Children's Heart Center, Charleston 29425., Swindle MM, Knick BJ, Case CL, Gillette PC
Jazyk: angličtina
Zdroj: Journal of investigative surgery : the official journal of the Academy of Surgical Research [J Invest Surg] 1994 May-Jun; Vol. 7 (3), pp. 243-8.
DOI: 10.3109/08941939409018289
Abstrakt: A protocol for high-dose narcotic anesthesia using sufentanil by intravenous infusion was developed in swine undergoing cardiac catheterization and intracardiac electrophysiologic studies. In experiments involving cardiac conduction system ablation, nine swine received intramuscular ketamine, 33 mg/kg, and intramuscular acepromazine, 1.1 mg/kg, as premedication. An infusion of sufentanil (15 mcg/kg/h) was started followed by a loading dose of sufentanil (7 mcg/kg) given as a bolus intravenously. A continuous infusion of sufentanil (15-30 mcg/kg/h) was used for maintenance anesthesia. Since the development of this protocol, we have been able to achieve stable hemodynamics and cardiac rhythms for intracardiac electrophysiologic studies.
Databáze: MEDLINE