Autor: |
Ademuyiwa O; Department of Biochemistry, College of Health Sciences, Ogun State University, Ago-Iwoye, Nigeria., Adesanya O, Ajuwon OR |
Jazyk: |
angličtina |
Zdroj: |
Human & experimental toxicology [Hum Exp Toxicol] 1994 Feb; Vol. 13 (2), pp. 107-9. |
DOI: |
10.1177/096032719401300208 |
Abstrakt: |
1. The hepatotoxic effect of CC14 was studied in the rat by using 3 well established liver function tests (plasma glucose, bilirubin and proteins) as indices of hepatic integrity. 2. The protective effect of vitamin C against this hepatotoxicity was also investigated. 3. CC14 (8 ml kg-1 body weight) caused a decrease in the levels of plasma conjugated bilirubin, glucose and protein. 4. Vitamin C (2 g kg-1 body weight) prevented liver damage induced by CC14. The possible mechanisms of protection are highlighted. |
Databáze: |
MEDLINE |
Externí odkaz: |
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