| Autor: |
Franke S; Center for Human Genetics and Genetic Counselling, University of Bremen, Germany., Klawitz I, Schnakenberg E, Rommel B, Van de Ven W, Bullerdiek J, Schloot W |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1994 Feb 28; Vol. 199 (1), pp. 52-5. |
| DOI: |
10.1006/bbrc.1994.1192 |
| Abstrakt: |
The NAT2 gene encodes for a polymorphic arylalkylamine N-acetyltransferase and thus accounts for the human N-acetylation polymorphism. By a NAT2-specific primer set we have screened a human chromosome 8-specific cosmid library. A positive cosmid clone was mapped by fluorescence in situ hybridization to 8p22. The polymerase chain reaction followed by restriction analysis of the PCR product was used to identify allele 2 to be contained in the cosmid clone. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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