Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar.

Autor: Giri OP; Department of Medicine, Darbhanga Medical College and Hospital, Laheriasaral, Darbhanga., Singh AN
Jazyk: angličtina
Zdroj: The Journal of the Association of Physicians of India [J Assoc Physicians India] 1994 Sep; Vol. 42 (9), pp. 690-1.
Abstrakt: One hundred cases of Indian Kala-azar unresponsive to sodium stibogluconate (SSG) were treated with amphotericin B. The drug was given in the dose schedule of 0.75 mg/kg body weight on alternate days intravenously dissolved in 5 percent dextrose solution. After 15 infusions given over a period of 30 days, all cases became clinically and parasitologically cured. Mild adverse reactions were noted during therapy. No relapse was observed at follow up after 12 months.
Databáze: MEDLINE