[Immune system indices for the prediction of the course of human immunodeficiency virus infection].

Autor: Gabrilovich DI, Serebrovskaia LV, Khabarova VV, Kravchenko AV, Avdeeva LA, Shalygina NB, Pokrovskiĭ VV
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1994 Aug-Sep; Vol. Suppl 1, pp. 114-8.
Abstrakt: In 25 persons having HIV infection with different dynamics of the progress of the disease the content of lymphocyte populations was studied (by the methods of rosette formation and with the use of monoclonal antibodies) and the rosette-forming and functional metabolic activity of neutrophils was determined. In comparison with patients with a stable course of HIV, patients with relatively rapid progress infection were found to have a significantly lesser amount of E-rosette-forming cells (E-RFC), active E-RFC, theophylline resistant E-RFC, E-rosette-forming neutrophils (E-RFN) and active E-RFN in combination with a significantly higher neutrophil and phosphatase activity and a significantly higher content of cation proteins. These characteristics may be used as criteria for prognosis of HIV infection progression.
Databáze: MEDLINE