Detection of lymph node metastases of squamous-cell cancer of the head and neck with FDG-PET and MRI.

Autor:	Braams JW; Department of Oral and Maxillofacial Surgery, National Research PET Center, Groningen, The Netherlands., Pruim J, Freling NJ, Nikkels PG, Roodenburg JL, Boering G, Vaalburg W, Vermey A
Jazyk:	angličtina
Zdroj:	Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 1995 Feb; Vol. 36 (2), pp. 211-6.
Abstrakt:	Unlabelled: The uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) in neck lymph nodes of twelve patients with a squamous-cell carcinoma of the oral cavity was studied with PET in order to detect and locate lymphogenic metastases. Methods: The results of FDG-PET imaging were compared with clinical, MRI and histopathologic findings. Standardized uptake values (SUV) were also calculated. Results: A sensitivity of 91% and a specificity of 88% were calculated for FDG-PET. In contrast, a sensitivity of 36% and a specificity of 94% were calculated for MRI. Calculated SUVs for reactive lymph nodes, metastatic lymph nodes and the primary tumor were undifferentiated. Conclusion: Using FDG-PET, lymph node metastases of squamous-cell carcinomas of the oral cavity can be visualized with a high sensitivity and specificity. FDG-PET can be an improvement in the evaluation of the neck.
Databáze:	MEDLINE
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