[Study of heat-protective effects of bromantane at various levels of overheating].

Autor: Badyshtov BA, Losev AS, Makhnycheva AL, Barchukov VG, Sytnik SI, Pastushenkov VA, Kolotilinskaia NV, Mironov SA, Morozov IS, Seredenin SB
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1995 Mar-Apr; Vol. 41 (2), pp. 54-7.
Abstrakt: The thermoprotective properties of bromantane were studied during overheating. Simultaneously with the known effects on heat exchange and sensitivity to high temperatures bromantane caused a decrease in ranges of heat tolerance, increased the rate of SVTK growth as well as altered protein metabolism and antioxidant protection and also affected the autonomic regulation of heat exchange which were essential in adaptation. At the same time, during ergothermal loading accompanied by any troubles in evaporation and heat exchange, marked thermoprotective efficiency of bromantane was compared for its ability to improve muscle dynamometry and hemodynamics as compared with control values.
Databáze: MEDLINE