| Autor: |
Pérez JL; Microbiology Service, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain., Niubò J, Ardanuy C, Carvajal A, García A, Salvà J, Martínez-Lacasa JT, Escribà JM, Martín R |
| Jazyk: |
angličtina |
| Zdroj: |
Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 1995 Jan; Vol. 21 (1), pp. 21-5. |
| DOI: |
10.1016/0732-8893(94)00144-l |
| Abstrakt: |
A total of 102 blood samples were used in a prospective parallel and blind study to evaluate three commercially available anti-pp65 monoclonal antibodies for cytomegalovirus antigenemia assay, at the dilutions recommended by their manufacturers. Cytomegalovirus was detected in 42 samples (41.2%), by either culture (32 samples; 76.2% of positive samples) or antigenemia (38 samples; 90.6%). Of the antigenemia-positive samples, 37 were detected by Monofluo kit CMV, which showed statistically significant differences when compared with the other reagents (Biosoft 1C3 and Clonab C10/C11), in either positivity rates (P < 0.004) or positive cell counts (P < 0.001). This reagent also gave better results in fluorescence quality than 1C3 and C10/C11. However, technical differences were not reflected in the clinical relevance of the antigenemia results. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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