Carbohydrates and drug discovery--the role of computer simulation.

Autor: Grootenhuis PD; Scientific Development Group, Organon International B.V., Oss, The Netherlands., van Boeckel CA, Haasnoot CA
Jazyk: angličtina
Zdroj: Trends in biotechnology [Trends Biotechnol] 1994 Jan; Vol. 12 (1), pp. 9-14.
DOI: 10.1016/0167-7799(94)90005-1
Abstrakt: Recent advances in the molecular modelling of carbohydrates have brought this technique to a level comparable with that of protein and nucleic acid simulations. After a brief introduction to the techniques used in the computer simulation of carbohydrates and carbohydrate interactions, an overview of applications in the field of carbohydrate-related drug discovery is presented.
Databáze: MEDLINE