| Autor: |
DeHoratius RJ, Strickland RG, Miller WC, Volpicelli NA, Gaeke RF, Kirsner JB, Williams RC Jr |
| Jazyk: |
angličtina |
| Zdroj: |
Lancet (London, England) [Lancet] 1978 May 27; Vol. 1 (8074), pp. 1116-9. |
| DOI: |
10.1016/s0140-6736(78)90298-2 |
| Abstrakt: |
Serum from patients with inflammatory bowel disease (I.B.D.) and their unaffected spouses bound significantly more synthetic single-stranded (poly.rA) and double-stranded (poly.rA.poly.rU) R.N.A. but not KB cell D.N.A. than did serum from age-matched controls and their spouses. Binding activity resided in Ig fractions and was predominantly of IgM class. A significant corelation was observed between the amount of double-stranded but not single-stranded R.N.A. bound by serum from patients and from their respective spouses. These findings provide indirect support for the presence of R.N.A. viruses in patients with I.B.D. and the transmission of such agents to their close personal contacts. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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