[Attempt to use the genetically engineered growth hormone SAIZEN in children with somatotropic insufficiency: results of clinical trials in Russia].

Autor: Dedov II, Peterkova VA, Goncharov NP, Buraia TI, Fofanova OV, Pankova SS, Bukhman AI
Jazyk: ruština
Zdroj: Problemy endokrinologii [Probl Endokrinol (Mosk)] 1994 Nov-Dec; Vol. 40 (6), pp. 30-4.
Abstrakt: The efficacy and safety of SAISEN, a recombinant human growth hormone obtained from mammalian cells, was tested in children with hypophyseal nanism. The treatment duration was 1 year. The results indicate that SAISEN (ARES-SERONO) is a highly effective and safe preparation of growth hormone, noticeably stimulating the growth rate both in previously untreated children with somatotropic insufficiency, and in those previously treated with STH preparations. Therapy with SAISEN was not associated with any side effects, as shown by both clinical and laboratory data.
Databáze: MEDLINE