| Autor: |
Toksoy HB; Department of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas, Turkey., Tanzer FN, Atalay A |
| Jazyk: |
angličtina |
| Zdroj: |
The Turkish journal of pediatrics [Turk J Pediatr] 1995 Jan-Mar; Vol. 37 (1), pp. 25-9. |
| Abstrakt: |
This study was performed in order to determine the effects of valproic acid on serum free carnitine, beta-hydroxybutyrate and blood amamonia. Serum free carnitine, beta-hydroxybutyrate and blood ammonia levels were measured in 24 epileptic children and in 24 age and sex-matched controls. The mean serum free carnitine level was significantly lower in patients taking valproic acid (33.5 +/- 13.1 nmol/ml) than in control subjects (50.8 +/- 14.6 nmol/ml) (p < 0.001). The mean blood ammonia level was significantly higher in patients receiving valproic acid (93.9 +/- 20.5 micrograms/dl) than in controls (79.6 +/- 21.4 micrograms/dl) (p < 0.002). The mean serum beta-hydroxybutyrate level was significantly lower in patients taking valproic acid (2.26 +/- 2.24 mg/dl) than in controls (4.38 +/- 2.43 mg/dl) (p < 0.001). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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