| Autor: |
Verhagen H; TNO Nutrition and Food Research Institute, Zeist, The Netherlands., Poulsen HE, Loft S, van Poppel G, Willems MI, van Bladeren PJ |
| Jazyk: |
angličtina |
| Zdroj: |
Carcinogenesis [Carcinogenesis] 1995 Apr; Vol. 16 (4), pp. 969-70. |
| DOI: |
10.1093/carcin/16.4.969 |
| Abstrakt: |
The effect of consumption of Brussels sprouts on levels of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) in human urine was investigated in 10 healthy, male, non-smoking volunteers. Following a 3 week run-in period, five volunteers continued on a diet free of cruciferous vegetables for a subsequent 3 week intervention period (control group), while the other five (sprouts group) consumed 300 g of cooked Brussels sprouts per day, at the expense of 300 g of a glucosinolate-free vegetable. Levels of 8-oxodG in 24 h urine samples were measured by HPLC. In the control group there was no difference between the two periods in levels of 8-oxodG (P = 0.72). In contrast, in the sprouts group the levels of 8-oxodG were decreased by 28% during the intervention period (P = 0.039). The present findings support the results of epidemiologic studies that consumption of cruciferous vegetables may result in a decreased cancer risk. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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