Ultradian variation in serum phosphate concentration in patients on haemodialysis.

Autor: Ring T; Medical Department C, Aalborg Hospital Syd, Denmark., Sanden AK, Hansen HH, Halkier P, Nielsen C, Fog L
Jazyk: angličtina
Zdroj: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 1995; Vol. 10 (1), pp. 59-63.
Abstrakt: To study how much the serum phosphate concentration could vary on the day before scheduled dialysis we obtained 24-37 timed measurements during 24 h in nine patients on maintenance haemodialysis. During the observation there was an increase in serum phosphate concentration of 0.239 +/- 0.022, P < 0.01). Surprisingly six of the nine patients exhibited nine statistically and clinically significant nadirs with decrements of 0.21 +/- 0.04 mmol/l against an intra-assay standard deviation of about 0.05 mmol/l. Five of the nadirs occurred at 11.40-14.50, mean 12.59, and three at 19.00-21.30, mean 20.00. We found no coinciding changes in the serum calcium concentration. These findings indicate that serum phosphate concentrations do not always reflect phosphorus balance or intake.
Databáze: MEDLINE