Iatrogenic transplantation of osteosarcoma.

Autor: Cole GW Jr; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Sindelar WF
Jazyk: angličtina
Zdroj: Southern medical journal [South Med J] 1995 Apr; Vol. 88 (4), pp. 485-8.
DOI: 10.1097/00007611-199504000-00023
Abstrakt: We report a case in which a patient having curettage and resection of a presumed benign lesion of the tibia (later recognized as osteosarcoma) had probable iatrogenic transplantation of tumor to the contralateral iliac crest, which had served as a donor site for bone chips used to pack the tibial lesion. The patient later had above-knee amputation for the primary tumor and eventually required contralateral hemipelvectomy when tumor developed in the iliac crest donor site. We discuss the literature of tumor transplantation and seeding in operative settings and stress the clinical importance of avoiding possible tumor contamination of operative fields by meticulous instrument changes and by isolation of multiple surgical fields.
Databáze: MEDLINE
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