| Autor: |
Dahlberg M; Department of Clinical Chemistry, Aker Hospital, Oslo, Norway., Odegaard OR, Try K, Amundsen T |
| Jazyk: |
angličtina |
| Zdroj: |
Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 1995 Apr; Vol. 55 (2), pp. 133-7. |
| DOI: |
10.3109/00365519509089605 |
| Abstrakt: |
We have evaluated an automated, simplified, turbidimetric method for the measurement of the C4b binding protein (C4bBP). A comparison with a manually performed electroimmunoassay in plasma samples referred for coagulation analysis (n = 80) revealed a correlation coefficient of 0.88. Lipaemic plasma is not suitable for analysis, whereas moderately haemolytic or icteric plasma may be used with the present method. In young and middle-aged patients (n = 33) investigated 3 or more months after an episode with thrombosis of unknown reason, the mean C4bBP concentration was not significantly different from the mean found in healthy controls (n = 38). This result is in accordance with the hypothesis that C4bBP is an acute phase reactant. The results indicate that the turbidimetric assay may replace the electroimmunoassay in clinical work. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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