Nuclear morphometry in differential diagnosis of renal oncocytoma and renal cell carcinoma.
| Autor: | Castrén JP; Department of Pathology, University of Turku, Finland., Kuopio T, Nurmi MJ, Collan YU |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of urology [J Urol] 1995 Oct; Vol. 154 (4), pp. 1302-6. |
| Abstrakt: | Purpose: Morphometric distinction of renal oncocytoma and renal cell carcinoma was attempted. Materials and Methods: Nuclear morphometric measurements were done from sections of 16 histologically diagnosed renal oncocytomas and renal cell carcinoma controls (grade 1 or 2, stage T1 to 2N0M0). Results: Oncocytomas could be distinguished from carcinomas on the basis of nuclear morphometry in more than 80% of the cases. Especially, the shape descriptors (form factors) were significantly different between oncocytomas and carcinomas. Conclusions: Morphometrically determined nuclear shape descriptors can be used to support diagnostic decisions in problematic cases. |
| Databáze: | MEDLINE |
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