[The effect of hydrodynamic conditions on the interferon-synthesizing activity of swine splenocytes in the production of alpha-interferon].

Autor: Dumanskiĭ VD, Povodzinskiĭ VN, Karlash IuV, Ivanenko VK, Seleznev AV, Tsygankov SP, Kishko IaG
Jazyk: ruština
Zdroj: Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) [Mikrobiol Z] 1995 May-Jun; Vol. 57 (3), pp. 71-7.
Abstrakt: Parameters of physical constituents of the agitation process and mass-exchange characteristics of the suggested bioreactor for suspension cultivation of pig splenocytes are determined. The effect of hydrodynamic conditions on viability and interferon-synthesizing activity of cells in production of alpha-interferon of pigs has been studied. The relation existing between interferonogenesis processes proceeding under suspension and under stationary biosynthesis has been analyzed by the pair correlation method.
Databáze: MEDLINE