| Autor: |
Nanan R; Children's Hospital, University of Würzburg, Germany., Scheurlen W, Gerlich M, Huppertz HI |
| Jazyk: |
angličtina |
| Zdroj: |
Annals of hematology [Ann Hematol] 1995 Aug; Vol. 71 (2), pp. 101-2. |
| DOI: |
10.1007/BF01699254 |
| Abstrakt: |
We report the case of a 12-year-old boy suffering from severe low-titer cold-hemagglutinin disease with excruciating colicky abdominal pain, jaundice, and acute hemolytic anemia requiring transfusion. Cold hemagglutinins of the IgM type and a positive direct antiglobulin test, predominantly against C3d, were found. Steroid pulse therapy with 20 mg/kg body wt. methylprednisolone for 3 consecutive days was given. Abdominal pain disappeared within 12 h of the first steroid infusion and hemolysis was halted. We conclude that a therapeutic trial with steroid pulse therapy in severe low-titer cold-hemagglutinin disease is warranted. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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