Effect of an acidic environment on the susceptibility of Helicobacter pylori to trospectomycin and other antimicrobial agents.

Autor: Debets-Ossenkopp YJ; Department of Clinical Microbiology, Free University Hospital, Amsterdam, The Netherlands., Namavar F, MacLaren DM
Jazyk: angličtina
Zdroj: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 1995 Apr; Vol. 14 (4), pp. 353-5.
DOI: 10.1007/BF02116532
Abstrakt: The susceptibility of 30 clinical isolates of Helicobacter pylori to trospectomycin, ampicillin, metronidazole, clarithromycin, azithromycin and clindamycin under varying pH conditions was evaluated. An acidic environment was shown to affect unfavourably the activity of all the antimicrobial agents tested. This pH effect was most marked for the two macrolides and for clindamycin.
Databáze: MEDLINE