[Diffuse pulmonary infiltration at the onset of Waldenström's disease].

Autor: Devouassoux G; Service de Pneumologie, Hôpital A. Michallon, CHU Grneoble., Pison C, Lantejoul S, Brambilla E, Brambilla C
Jazyk: francouzština
Zdroj: Revue des maladies respiratoires [Rev Mal Respir] 1995; Vol. 12 (3), pp. 308-10.
Abstrakt: The case of an 52 years old female presenting dyspnea and pulmonary infiltration is reported. A transbronchial biopsy showing a lymphomatous infiltrate with immunohistochemistry using anti-IgM antibody on paraffine embedded section helped to diagnose. A monoclonal increase in seric immunoglobin M, led to the diagnosis of Waldrenström's macroglobulinemia. An initial therapeutic response to Chlorambucil was obtained. But a quick recurrence was observed, with an increase of seric IgG.
Databáze: MEDLINE