| Autor: |
Róna K; Haynal Imre University of Health Sciences, Ist Department of Medicine, Budapest, Hungary., Ary K, Szüts I, Kovács L, Gachályi B |
| Jazyk: |
angličtina |
| Zdroj: |
Acta medica Hungarica [Acta Med Hung] 1994; Vol. 50 (1-2), pp. 65-74. |
| Abstrakt: |
The authors studied the distribution of the paracetamol conjugation in a Hungarian population (53 adult Caucasian persons). The data indicated that the excretion of paracetamol glucuronide and sulphate were not normally distributed. Bimodality were apparent in both conjugation pathways: 15.1% of subjects was relatively extensive glucuronidators, and the 24.5% of subjects was extensive sulphatators. Monitoring the ratios of various urinary paracetamol conjugates/paracetamol may be useful as a tool for determining the glucuronide and sulphate conjugation capacity in humans. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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