Primary fallopian tube adenocarcinoma: clinical complete response after salvage treatment with high-dose paclitaxel.

Autor: Tresukosol D; Chulalongkorn University Hospital, Bangkok, Thailand., Kudelka AP, Edwards CL, Fromm GL, Mante R, Kavanagh JJ
Jazyk: angličtina
Zdroj: Gynecologic oncology [Gynecol Oncol] 1995 Aug; Vol. 58 (2), pp. 258-61.
DOI: 10.1006/gyno.1995.1222
Abstrakt: This Case Report describes a patient with primary fallopian tube cancer who had a late recurrence of pelvic disease following adjuvant chemotherapy for early-stage disease. Secondary cytoreductive surgery was suboptimal. The bulky residual disease was refractory to platinum-based therapy. Extension of the disease to the retroperitoneum resulted in obstructed venous return, ureteral obstruction, and renal infection. The latter necessitated a third laparotomy and a nephrectomy. Upon recovery from surgery and failure of platinum reinduction, the patient was treated with high-dose paclitaxel. The large pelvic mass regressed rapidly and completely. Current chemotherapy for fallopian tube cancer is briefly reviewed.
Databáze: MEDLINE