| Autor: |
Aglailar Setien A; Unidad de Investigación Médica en Inmunología, Centro Médico Nacional Siglo XXI, México, D.F., Kretschmer R, Espinosa Larios EL |
| Jazyk: |
angličtina |
| Zdroj: |
Archives of medical research [Arch Med Res] 1995 Summer; Vol. 26 (2), pp. 173-7. |
| Abstrakt: |
The influence of methylphenidate (MP) upon cell fusion, hemagglutination and hemolysis induced by paramyxovirus was evaluated in vitro. A direct correlation between MP concentrations (range 40 mg/ml to 1.25 mg/ml) and hemagglutination and hemolysis induced by Newcastle disease virus (NDV) was found. Furthermore, MP (500 micrograms/ml) increased formation of the syncytia by LPM paramyxovirus in PK-15 cells. It is fair to speculate that MP leads to activation of the F and/or HN proteins in paramyxovirus by mechanisms other than proteolytic cleavage. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
