| Autor: |
Zölzer F; Institut für Medizinische Strahlenbiologie, Universitätsklinikum Essen, Germany., Streffer C |
| Jazyk: |
angličtina |
| Zdroj: |
Radiation research [Radiat Res] 1995 Jul; Vol. 143 (1), pp. 98-101. |
| Abstrakt: |
The proliferation of human melanoma cells in vitro during the first 3 days after irradiation and/or hyperthermia was followed by two-parameter flow cytometry combining cell cycle analysis on the basis of DNA content with Ki-67 antibody labeling. It was found that cells arrested or delayed in the S and G2 phases of the cell cycle were Ki-67-positive in spite of the antigen's very short half-life. Thus Ki-67 staining failed to reflect those changes in cell proliferation which typically occur in the course of a fractionated radiotherapy as well as those expected in the case of hyperthermia or a combined treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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