| Autor: |
Beanan MJ; Department of Microbiology and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA., Bailey GB |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of eukaryotic microbiology [J Eukaryot Microbiol] 1995 Sep-Oct; Vol. 42 (5), pp. 632-6. |
| DOI: |
10.1111/j.1550-7408.1995.tb05919.x |
| Abstrakt: |
An Entamoeba histolytica gene (hex-A1) that encodes subunit A of the lysosomal enzyme beta-hexosaminidase has been cloned and sequenced. The inferred 59 kDa hex-A1 protein has the same molecular weight and 32% amino acid residue identity with the human and mouse proteins and 28% residue identity with the Dictyostelium protein. Northern blot analysis identified a mRNA of approximately 1.6 kb, which is in agreement with the expected size of a mRNA encoding the 522 amino acid hex-A1 protein. Southern blot analysis indicated the presence of at least two beta-hexosaminidase A subunit genes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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