| Autor: |
Somoza JR; Department of Chemistry and Lawrence Berkeley Laboratory, University of California, Berkeley 94720, USA., Szöke H, Goodman DM, Béran P, Truckses D, Kim SH, Szöke A |
| Jazyk: |
angličtina |
| Zdroj: |
Acta crystallographica. Section A, Foundations of crystallography [Acta Crystallogr A] 1995 Sep 01; Vol. 51 ( Pt 5), pp. 691-708. |
| DOI: |
10.1107/s0108767395002315 |
| Abstrakt: |
The holographic method makes use of partially modeled electron density and experimentally measured structure-factor amplitudes to recover electron density corresponding to the unmodeled part of a crystal structure. This paper describes a fast algorithm that makes it possible to apply the holographic method to sizable crystallographic problems. The algorithm uses positivity constraints on the electron density and can incorporate a 'target' electron density, making it similar to solvent flattening. The potential for applying the holographic method to macromolecular X-ray crystallography is assessed using both synthetic and experimental data. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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