| Autor: |
Coburn SP; Biochemistry Department, Fort Wayne State Developmental Center, IN, USA., Thampy KG, Lane HW, Conn PS, Ziegler PJ, Costill DL, Mahuren JD, Fink WJ, Pearson DR, Schaltenbrand WE, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of clinical nutrition [Am J Clin Nutr] 1995 Nov; Vol. 62 (5), pp. 979-83. |
| DOI: |
10.1093/ajcn/62.5.979 |
| Abstrakt: |
Vitamin B-6 metabolism in 10 volunteers during 21 d of total fasting was compared with results from 10 men consuming a diet low only in vitamin B-6 (1.76 mumol/d) and with men consuming a normal diet during bed rest. At the end of the fast mean plasma concentrations of vitamin B-6 metabolites and urinary excretion of 4-pyridoxic acid tended to be higher in the fasting subjects than in the low-vitamin B-6 group. The fasting subjects lost approximately 10% of their total vitamin B-6 pool and approximately 13% of their body weight. The low-vitamin B-6 group lost only approximately 4% of their vitamin B-6 pool. Compared with baseline, urinary excretion of pyridoxic acid was significantly increased during 17 wk of bed rest. There was no increase in pyridoxic acid excretion during a second 15-d bed rest study. These data suggest the possibility of complex interactions between diet and muscle metabolism that may influence indexes that are frequently used to assess vitamin B-6 status. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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