The pseudocalanolides: structure revision of calanolides C and D.

Autor: McKee TC; Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick, Maryland 21702-1201, USA., Cardellina JH 2nd, Dreyer GB, Boyd MR
Jazyk: angličtina
Zdroj: Journal of natural products [J Nat Prod] 1995 Jun; Vol. 58 (6), pp. 916-20.
DOI: 10.1021/np50120a015
Abstrakt: Nmr spectra of synthetic structures corresponding to those initially reported for natural compounds calanolide C [1] and calanolide D [2] showed some subtle differences from those of the natural products. Further analysis has resulted in revision of the structures of the natural compounds, now renamed pseudocalanolides C [3] and D [4]. The absolute stereochemistry of pseudocalanolide C was established as [6S, 7S, 8R] using the modified Mosher's method.
Databáze: MEDLINE