Beta-HCG concentration in peritoneal fluid and serum in ectopic and intrauterine pregnancy.

Autor: Oettinger M; Department of Obstetrics and Gynecology, Western Galilee Regional Hospital, Nahariya, Israel., Odeh M, Tarazova L, Snitkovsky T, Ophir E
Jazyk: angličtina
Zdroj: Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 1995 Mar; Vol. 74 (3), pp. 212-5.
DOI: 10.3109/00016349509008941
Abstrakt: Objective: To evaluate the significance of beta-HCG levels in peritoneal fluid and serum in the diagnosis of ectopic pregnancy. STUDY DESIGN SETTING: Obstetrics and Gynecology department of a regional general hospital.
Subjects: Sixty-two women who presented with a differential diagnosis of ectopic pregnancy vs. nonviable intrauterine pregnancy.
Interventions: All patients underwent D & C and culdocentesis. beta-HCG was measured in simultaneously obtained peritoneal fluid (PF) and serum (S), and the PF/S ratio calculated.
Results: Twenty-three patients had an ectopic pregnancy (Group I). All 23 had higher beta-HCG concentrations in the PF than in the serum, with a mean PF/S ratio of 19.1 +/- 16.9. Twenty-four patients had an intrauterine pregnancy (Group II). The beta-HCG levels in the PF and serum were similar (mean PF/S 1.1 +/- 0.2). The difference in PF/S ratio between groups I and II was statistically significant (p < 0.001).
Conclusion: The measurement of beta-HCG in peritoneal fluid and serum is a useful diagnostic tool in differentiating ectopic from intrauterine pregnancy.
Databáze: MEDLINE