Carcinoma of the prostate: race as a prognostic indicator in definitive radiation therapy.
| Autor: | Kim JA; Department of Radiation Oncology, Eastern Virginia Medical School, Norfolk 23507., Kuban DA, el-Mahdi AM, Schellhammer PF |
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| Jazyk: | angličtina |
| Zdroj: | Radiology [Radiology] 1995 Feb; Vol. 194 (2), pp. 545-9. |
| DOI: | 10.1148/radiology.194.2.7529936 |
| Abstrakt: | Purpose: To characterize the racial differences in prognostic factors and treatment outcome for patients undergoing radiation therapy for carcinoma of the prostate. Materials and Methods: From January 1975 through December 1989, 489 white and 157 black men with carcinoma of the prostate underwent irradiation. Factors analyzed were patient age, tumor stage and grade, prostate-specific antigen (PSA) levels, and disease-control and survival rates. Results: More black patients than white patients were found to have poorly differentiated tumors. Black patients had higher PSA levels before and after treatment, resulting in a higher distant failure rate and poorer overall, cause-specific, and disease-free survival rates. Conclusion: Black men have more aggressive prostatic tumors, a higher rate of metastasis, and a poorer survival rate than do white men. |
| Databáze: | MEDLINE |
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